A study in mice suggests that faecal microbiota transplantation could have unexpected effects on other areas of the digestive system
An international study has warned of the potential risks of widespread use of faecal microbiota transplantation without taking into account the region of the intestine where the transferred microbes arrive. The experiment, conducted on mice and human tissue samples, showed that the microbes from the transplant—mostly anaerobic microbes from the colon—colonised the small intestine, persisted there for months and modified that new environment, causing changes in the host's metabolism. According to the authors, whose study is published in the journal Cell, this may have long-lasting and unforeseen consequences, as well as imbalances in the intestinal ecosystem of patients.
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