Barcelona Institute for Global Health (ISGlobal)

Global vaccination efforts have achieved an 88% reduction in measles deaths between 2000 and 2024, and nearly 59 million lives have been saved by the vaccine since the beginning of the century, according to a new report from the World Health Organization (WHO). However, an estimated 95,000 people—mostly children under the age of five—died from measles in 2024, a disease that could be prevented with an effective, low-cost vaccine. Although the death toll is one of the lowest in this period, measles cases are on the rise worldwide, with an estimated 11 million infections in 2024, nearly 800,000 more than pre-pandemic levels in 2019. Specifically, cases in Europe increased by 47% between 2019 and 2024.

The Pfizer-BioNTech COVID-19 vaccine has been linked to rare cases of heart inflammation in children and young people. The largest study of these risks in children, published in The Lancet Child & Adolescent Health, concluded that receiving the vaccine is associated with a risk of developing myocarditis or pericarditis within six months of 0.85 additional cases per 100,000 vaccinated children; while after COVID-19 infection, the risk is 2.24 additional cases per 100,000. The study used data from 98% of the British population under the age of 18 (almost 14 million) between January 2020 and December 2022.

Childhood vaccination rates have increased modestly worldwide in 2024, without reaching their pre-COVID-19 pandemic levels, according to data from the WHO and UNICEF. For example, global measles vaccination coverage rose by one percentage point from the previous year, reaching 84% of girls and boys who had received one dose in 2024, compared to 86% in 2019.

A team from the United States has analysed data on modes of transport in more than 11,500 cities in 121 countries around the world, including Spain, representing 41% of the world's population. In addition to studying the factors that most influence the proportion of journeys made on foot or by bicycle, they estimate that if each city analysed increased the extent of its cycling network to the level of Copenhagen (Denmark), private vehicle emissions would be reduced by 6% and the public health benefits would be equivalent to around £37 billion. The results are published in the journal PNAS.

An international study has warned of the potential risks of widespread use of faecal microbiota transplantation without taking into account the region of the intestine where the transferred microbes arrive. The experiment, conducted on mice and human tissue samples, showed that the microbes from the transplant—mostly anaerobic microbes from the colon—colonised the small intestine, persisted there for months and modified that new environment, causing changes in the host's metabolism. According to the authors, whose study is published in the journal Cell, this may have long-lasting and unforeseen consequences, as well as imbalances in the intestinal ecosystem of patients.

The Member States of the World Health Organisation (WHO), meeting on Monday in Committee A of the World Health Assembly, approved a resolution calling for the adoption of a historic global pact to make the world safer from future pandemics. On Tuesday, the Assembly, in plenary session, adopted by consensus the world's first agreement on pandemics.

An international team has analyzed the sudden changes in temperature that occurred in the world between 1961 and 2023. Their conclusions are that more than 60% of the regions included in the analysis - including Western Europe - have experienced an increase in the frequency and intensity of these sudden changes, which can endanger health, agriculture or infrastructures. Moreover, the trend will continue to rise as a result of climate change. The results are published in the journal Nature Communications.

The new US president, Donald Trump, announced on his first day that the country will leave the World Health Organisation (WHO) within the next twelve months. The reasons behind the decision, according to him, are the ‘mismanagement of the covid-19 pandemic and other global health crises’, as well as ‘disproportionate payments compared to other countries’ dues’.

A team led by the CEU San Pablo University has analysed the role of vaccination against influenza on the risk of infection and mortality. The meta-analysis, published in European Respiratory Review, includes 192 articles from different countries over the last 20 years and includes data from more than 6.5 million patients. The results show that the level of protection varies according to age group and influenza subtype. Although it does not reduce the risk of infection for influenza A H3N2 in those over 65 years of age, nor does it show a reduction in mortality for influenza B - which is less associated with mortality than influenza A - overall, vaccination is shown to be effective in both preventing infection and reducing mortality.

The RH5.1/Matrix-M vaccine is effective and safe against malaria, according to a phase 2b clinical trial in infants in Burkina Faso published in The Lancet Infectious Diseases. Two other vaccines are already approved against malaria, a disease caused by the Plasmodium falciparum parasite, but this one acts at a different stage of the disease: when the malaria parasite is present in the blood. The other two vaccines attack the parasite when reaches the liver.