Barcelona Institute for Global Health (ISGlobal)

An international team has analyzed the sudden changes in temperature that occurred in the world between 1961 and 2023. Their conclusions are that more than 60% of the regions included in the analysis - including Western Europe - have experienced an increase in the frequency and intensity of these sudden changes, which can endanger health, agriculture or infrastructures. Moreover, the trend will continue to rise as a result of climate change. The results are published in the journal Nature Communications.

The new US president, Donald Trump, announced on his first day that the country will leave the World Health Organisation (WHO) within the next twelve months. The reasons behind the decision, according to him, are the ‘mismanagement of the covid-19 pandemic and other global health crises’, as well as ‘disproportionate payments compared to other countries’ dues’.

A team led by the CEU San Pablo University has analysed the role of vaccination against influenza on the risk of infection and mortality. The meta-analysis, published in European Respiratory Review, includes 192 articles from different countries over the last 20 years and includes data from more than 6.5 million patients. The results show that the level of protection varies according to age group and influenza subtype. Although it does not reduce the risk of infection for influenza A H3N2 in those over 65 years of age, nor does it show a reduction in mortality for influenza B - which is less associated with mortality than influenza A - overall, vaccination is shown to be effective in both preventing infection and reducing mortality.

The RH5.1/Matrix-M vaccine is effective and safe against malaria, according to a phase 2b clinical trial in infants in Burkina Faso published in The Lancet Infectious Diseases. Two other vaccines are already approved against malaria, a disease caused by the Plasmodium falciparum parasite, but this one acts at a different stage of the disease: when the malaria parasite is present in the blood. The other two vaccines attack the parasite when reaches the liver.

Men and women could develop Alzheimer’s disease through different mechanisms. Understanding these differences is essential to design specific interventions and to treat the disease effectively. In an article published in Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, a group of researchers, including myself, have highlighted the urgency of adding a sex and gender approach to the studies on this pathology.

A new web-based tool analyzes major cities like Tokyo, Paris, Atlanta or Barcelona to see how close they are to the 15-minute city concept, where residents take less than those minutes to access essential services by foot, bike, or public transport. According to the study, published in Nature Cities, few cities fit this concept. The tool, which is freely accessible and uses data from 10,000 cities sourced from the open-source packages GeoPandas and OpenStreetMap, could be useful for developing action plans and estimating how viable it is to transform certain cities to follow this model.

Heat-related mortality in Europe would have been 80% higher last year without recent adaptation measures to rising temperatures, such as changes in infrastructure and public behaviour, according to a study led by ISGlobal. The study, published in Nature Medicine, estimates that more than 47,000 deaths were related to the heat in 35 European countries in 2023 - the second highest number in the 2015-2023 period, behind 2022. Heat-related mortality was highest in southern European countries including Spain (175 deaths per million people), Italy (209) and Greece (393). 

The use of the antidepressants escitalopram, paroxetine, and duloxetine is associated with greater weight gain than the use of sertraline, according to the results of an analysis comparing data from more than 183,000 adults treated with one of eight types of antidepressants. Among these, bupropion is associated with the least weight gain, concludes the study, which is published in Annals of Internal Medicine.

A study in England has found a link between increased exposure to air pollution during early life and the risk of developing psychotic disorders and depression during youth. In addition, greater exposure to noise during childhood and adolescence was associated with an increased risk of anxiety. The results of the study, which collected data from more than 9,000 people, are published in the journal JAMA Network Open. 

A study published in the journal Environmental Health Perspectives has analysed hospital admissions in 48 Spanish provinces during the months of June to September between 2006 and 2019. Its results, discussed at a briefing organised by Science Media Centre Spain, show that high temperatures increase admissions for issues related to obesity and renal and urinary insufficiency, among other causes.