Barcelona Institute for Global Health (ISGlobal)

The RH5.1/Matrix-M vaccine is effective and safe against malaria, according to a phase 2b clinical trial in infants in Burkina Faso published in The Lancet Infectious Diseases. Two other vaccines are already approved against malaria, a disease caused by the Plasmodium falciparum parasite, but this one acts at a different stage of the disease: when the malaria parasite is present in the blood. The other two vaccines attack the parasite when reaches the liver.

Men and women could develop Alzheimer’s disease through different mechanisms. Understanding these differences is essential to design specific interventions and to treat the disease effectively. In an article published in Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, a group of researchers, including myself, have highlighted the urgency of adding a sex and gender approach to the studies on this pathology.

A new web-based tool analyzes major cities like Tokyo, Paris, Atlanta or Barcelona to see how close they are to the 15-minute city concept, where residents take less than those minutes to access essential services by foot, bike, or public transport. According to the study, published in Nature Cities, few cities fit this concept. The tool, which is freely accessible and uses data from 10,000 cities sourced from the open-source packages GeoPandas and OpenStreetMap, could be useful for developing action plans and estimating how viable it is to transform certain cities to follow this model.

Heat-related mortality in Europe would have been 80% higher last year without recent adaptation measures to rising temperatures, such as changes in infrastructure and public behaviour, according to a study led by ISGlobal. The study, published in Nature Medicine, estimates that more than 47,000 deaths were related to the heat in 35 European countries in 2023 - the second highest number in the 2015-2023 period, behind 2022. Heat-related mortality was highest in southern European countries including Spain (175 deaths per million people), Italy (209) and Greece (393). 

The use of the antidepressants escitalopram, paroxetine, and duloxetine is associated with greater weight gain than the use of sertraline, according to the results of an analysis comparing data from more than 183,000 adults treated with one of eight types of antidepressants. Among these, bupropion is associated with the least weight gain, concludes the study, which is published in Annals of Internal Medicine.

A study in England has found a link between increased exposure to air pollution during early life and the risk of developing psychotic disorders and depression during youth. In addition, greater exposure to noise during childhood and adolescence was associated with an increased risk of anxiety. The results of the study, which collected data from more than 9,000 people, are published in the journal JAMA Network Open. 

A study published in the journal Environmental Health Perspectives has analysed hospital admissions in 48 Spanish provinces during the months of June to September between 2006 and 2019. Its results, discussed at a briefing organised by Science Media Centre Spain, show that high temperatures increase admissions for issues related to obesity and renal and urinary insufficiency, among other causes. 

Twenty-three per cent of the world's population over the age of 69 will be living with acute heat exposure by 2050, compared to 14 per cent in 2020, according to a study published in Nature Communications. The research highlights southern Europe, parts of North and South America, Southeast Asia and all of Australia as areas of ‘increasing stress’, where higher heat exposure overlaps with an increasingly ageing population. The effects will be most severe in Asia and Africa, according to the study. 

Until now, it was thought that the risk of heat-related death in Spain had decreased among older people. But what if we take into account the increase in longevity? Has it decreased as much as the studies suggested? In this case it is useful to use the concept of prospective age, i.e. the years we hypothetically have left to live, rather than the years we have lived. 

Following the agreement reached a few months ago between the European Parliament and Council, in today’s plenary session the European Parliament has approved a provisional political agreement with EU countries that includes new requirements to improve air quality by 2030. The agreement sets stricter targets and limits for several pollutants that have a serious impact on health, including particulate matter (PM2.5, PM10), NO2 (nitrogen dioxide) and SO2 (sulfur dioxide). Before being published in the Official Journal of the European Union, the law now must be adopted by the Council. EU countries will have two years to implement the new standards