Ignacio Morgado

Brain maturation is measured by the thickness of the cortex. It is known that stress accelerates cortical thinning, which is associated with a higher risk of developing neuropsychiatric disorders. A study published in PNAS analyzes MRI data collected from 160 adolescents before COVID-19 and from 130 of them after the measures implemented during the pandemic. The comparison of brain structure before and after reveals accelerated cortical thinning which, measured in terms of equivalent years of brain development, was 4.2 years in girls and 1.4 years in boys.brain maturity

An international team of researchers has studied 241 brain-damaged people apparently unable to respond to external stimuli. Using techniques such as functional magnetic resonance imaging and electroencephalogram, they have detected signs of brain activity in 25 % of them that, according to the authors, ‘suggest that they may be interacting with the outside world’. The results are published in the journal NEJM. 

The PsychENCODE consortium, established in 2015 and dedicated to illuminating the molecular mechanisms underlying schizophrenia, bipolar disorder, and autism spectrum disorder, presents findings based on the examination of human brains at the cellular level. The studies are published today in the journals Science, Science Translational Medicine and Science Advances.

The time adolescents spend on social media is one of the least influential factors for their mental health, according to a study published in Nature Mental Health. The analysis attempts to untangle the complex web of risk factors and protective factors, using data from more than 12,000 young people in the UK. Among the factors studied, it concludes that bullying, lack of family support and school work dissatisfaction are more influential than time spent on social media. According to the study, life dissatisfaction and lack of family support are the most influential factors for girls and boys, respectively. 

Beta-blockers (β-blockers) are drugs to treat heart conditions that are also used for anxiety. According to research published in PLOS Medicine, periods of treatment with these drugs are associated with a lower risk of being charged by the police with a violent crime - a 13% lower risk than periods without treatment. The research, which included nearly 1.5 million people in Sweden between 2006 and 2013, does not support the use of these drugs to treat anxiety.

Constant checking of social media activity in early adolescence is associated with changes in the brain's sensitivity to rewards and punishments. This is the conclusion of a study involving 169 12- and 13-year-old students in the United States with Facebook, Instagram and Snapchat profiles, according to JAMA Pediatrics.

A study in mice published in the journal Nature has analysed the different responses to aggression and the consequences for subsequent behaviour. In general, animals that confronted the aggressor developed greater resilience than those that fled or avoided the aggressor, and the gain was greater as brain circuits associated with dopamine were activated.