chemistry

In 2015, the human health impact of exposure to certain chemicals cost the equivalent of $1.5 trillion, says a study published in PNAS. The study estimates cases of ischaemic heart disease and stroke associated with bisphenol A (BPA) exposure; deaths of 55-64 year olds associated with di(2-ethylhexyl) phthalate (DEHP) exposure; and cognitive losses in children of mothers exposed to brominated flame retardants (PBDEs).

A research team describes in the journal Science how to create organic molecules whose geometry breaks the so-called Bredt's rule. According to this 1924 rule, double bonds between two carbon atoms cannot exist at certain positions in a molecule. Until now, this rule has limited the types of molecules that scientists can imagine and make.

Current carbon capture technologies to mitigate climate change only work well when applied to concentrated sources, such as power plant exhaust gases. An international team of researchers has developed a new method using a special porous material capable of capturing CO₂ directly from the air, despite its low concentration. According to the authors, who publish their results in the journal Nature, this technology ‘represents a significant step towards clean air’.

For the treatment of many diseases it is necessary to use large molecules that do not resist the digestion process and must be injected. Now, a group of scientists at the Institute of Chemical Sciences and Engineering in Lausanne (Switzerland) has developed a method for synthesizing a type of protein called cyclic peptides, capable of binding to varied and complex targets, and they have done so in a way that makes them capable of being administered orally. According to the press release accompanying the publication, this opens "a new era in drug development".

The Royal Swedish Academy of Sciences has awarded the Nobel Prize in Chemistry 2023 to Moungi G. Bawendi, Louis E. Brus, and Alexei I. Ekimov "for the discovery and synthesis of quantum dots." Quantum dots are tiny nanoparticles that diffuse their light from televisions and LED lights, and can also guide surgeons when removing tumor tissue, among many other applications.

A research team in Belgium found perfluoroalkylated and polyfluoroalkylated substances (PFAS) in drinking straws. The research, published in the journal Food Additives & Contaminants, analysed the presence of these persistent and potentially harmful compounds in 39 types of straws purchased from different shops, supermarkets or fast food chains. These substances were most prevalent in paper and bamboo straws, followed by plastic and glass straws. They were not detected in stainless steel straws.

A research team describes in Nature the presence outside the solar system of CH3+, a cation that could react with other molecules to form complex organic molecules. Its role in interstellar organic chemistry was described decades ago, but until now it had not been observed outside the solar system. The team, which includes co-authors from the CSIC's Institute of Fundamental Physics and the National Astronomical Observatory in Madrid, based their work on observations from James Webb Telescope.

A Japanese research team has announced in Nature Communications that it found uracil, a component necessary to form RNA, in a small sample collected from the asteroid Ryugu. According to the authors, these results indicate that these molecules of prebiotic interest were commonly formed on asteroids like Ryugu, and reached the early Earth with the impact of these bodies. The sample was collected by the Japan Aerospace Exploration Agency's Hayabusa2 robotic spacecraft, which returned to Earth in December 2020.

US scientists have found perfluoroalkylated and polyfluoroalkylated substances (PFASs) in sewage sludge from toilet paper waste. The research, published in the journal Environmental Science & Technology Letters, analysed the presence of these persistent and potentially harmful compounds in toilet paper rolls sold in North, South and Central America, Africa and Western Europe. These substances were compared with those detected in samples of sewage sludge from sewage treatment plants in the United States.

The Nobel Prize in Chemistry 2022 has been awarded to Barry Sharpless and Morten Meldal for laying the foundations of click chemistry, which quickly and efficiently joins molecular building blocks; and to Carolyn Bertozzi, who pioneered bioorthogonal reactions, which use this technique inside living organisms without altering the chemistry of the cell.