Based on a defense protein of the strawberry anemone, researchers from the Barcelona Supercomputing Center, CSIC and the Complutense University of Madrid have designed, through artificial intelligence and the use of supercomputers, an artificial protein capable of degrading PET micro and nanoplastics, such as those used in bottles. According to the authors, its efficiency is between 5 and 10 times higher than that of the proteins currently used and it works at room temperature. The results are published in the journal Nature Catalysis.
Reaction: Meta publishes ESMFold, a model that predicts the structure of hundreds of millions of proteins
Meta has applied language modelling to predict the structure of a large collection of proteins. The model, called ESMFold, is being presented this week in the journal Science after being published on the bioRxiv preprint article server in December 2022. EMSFold is faster than similar models such as AlphaFold, developed by Google's DeepMind and EMBL's European Bioinformatics Institute. The sequences of more than 617 million proteins - of which more than a third are predicted with a high degree of confidence - are published in open access in the ESM Metagenomic Atlas.
The database with the predicted 3D structures of almost all catalogued proteins has just been published. The impact on biology is incalculable, from the development of a vaccine against malaria, to understanding Parkinson's disease, the health of honeybees or the fight against plastic pollution.