Based on a defense protein of the strawberry anemone, researchers from the Barcelona Supercomputing Center, CSIC and the Complutense University of Madrid have designed, through artificial intelligence and the use of supercomputers, an artificial protein capable of degrading PET micro and nanoplastics, such as those used in bottles. According to the authors, its efficiency is between 5 and 10 times higher than that of the proteins currently used and it works at room temperature. The results are published in the journal Nature Catalysis.
A review examines the role of domestic and semi-domestic animals, such as cats, in the emergence of potential zoonoses due to their close contact with humans. The paper, published in the journal Science Translational Medicine, concludes that companion animal health risks will become increasingly problematic with climate change and rapid urbanisation.
An international group of scientists has studied epidemiological data since 2005 and more than 10,000 viral genomes to conclude that the epicentre of H5 avian influenza has shifted from Asia to parts of Africa and Europe. New lineages have emerged from these regions between 2020 and 2022, which evolved by genetic reassortment with low pathogenic viral variants as they spread. According to the authors, who publish their findings in the journal Nature, the increasing persistence of avian influenza in wild bird populations may be driving the evolution and spread of new strains.
A meta-analysis, pooling the results of 40 previous studies - involving more than 310,000 children and adolescents in total - concludes that treatment rates for mental disorders in these age groups are "generally low, especially for depression and anxiety". The research, published in JAMA Network Open, shows that the treatment rate for any mental disorder is 38%, ranging from 31% for anxiety, 36% for depression, 49% for conduct disorders and 58% for attention deficit hyperactivity disorder (ADHD).
Synthetic embryos, artificial placentas, genome editing... Advances in biology and medicine keep bringing up thorny ethical questions. Here's an overview of Spain’s many bioethics committees, which can be useful resources for journalists.
Spermidine is a naturally occurring compound that has been linked to increased longevity in some organisms. New research shows that supplementation with this compound improves oocyte quality and fertility in older female mice. If its action and safety in humans is confirmed, the authors argue that it could serve as a therapeutic strategy to "improve the reproductive outcome of older women, either through natural pregnancy or assisted reproductive technologies". The results are published in the journal Nature Aging.
The Science group of journals publishes several parts of a high-resolution atlas of human brain cells, the largest 'map' of its kind to date. It is a series of papers from an international mega-project, the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative - Cell Census Network (BICCN), launched in 2017 to study brain cell types and their functions in humans, non-human primates and rodents. The data "will now allow researchers to address fundamental scientific questions about the human brain and its genetic organisation," states the introduction to the journal's special issue.
Currently, when an organ transplant is performed, the patient has to take immunosuppressive drugs to prevent his or her system from rejecting the new organ. These drugs must be taken for life and have numerous side effects. In a phase 1 clinical trial, researchers gave patients receiving a liver transplant regulatory dendritic cells derived from the original donor, with the hypothesis that these cells could 'teach' the recipient's immune system to tolerate the new organ. The research, published in Science Translational Medicine, suggests that this treatment could reduce or even eliminate the need for long-term use of immunosuppressants.
Floods in Libya and Greece, fires in Australia or earthquakes in Morocco. Disasters are on the rise, partly because climate change is affecting the frequency and intensity of some of them. The media often use the term 'natural disaster' to describe them, something a team of crisis and disaster specialists is trying to change.
Living as a private renter is associated with faster biological ageing than owning a home, according to a study using a UK database with data available on 1,420 people. The team, whose research is published in the Journal of Epidemiology and Community Health, used DNA methylation data - chemical modifications - to measure people's biological age, and says this correlation is stronger than the association between biological ageing and unemployment, or having been a smoker. Apart from blood samples from the database, the research also used historical data from a national survey.