nutrition

A study published in PLOS Biology analysed whether supplementation with zinc, serine and branched-chain amino acids —valine, isoleucine and leucine— improves autism-related symptoms in three mouse models. These nutrients are believed to regulate synaptic formation and activity. The results show that the combination of the three nutrients, at low doses for seven days, improved affected brain traits —such as hyperactivity and hyperconnectivity of the amygdala— and the social behaviour of the animals. Individual supplementation did not show such improvements. 

Three articles with Spanish participation, published in The Lancet, review the evidence that ultra-processed foods are worsening diet quality and displacing the consumption of fresh and minimally processed foods. Furthermore, they warn that their consumption is linked to a higher risk of multiple chronic diseases. According to the authors, who also review the associated policies and commercial factors, only a coordinated global response can combat the strategy of the companies that market these products.

The use of creatine among athletes is not new, although its consumption has become popular on social media. We answer questions about this compound with the help of experts in nutrition, sports and dietetics.

The Planetary Health Diet promotes environmentally sustainable consumption, based, among other things, on increasing vegetable intake and reducing dairy and red meat consumption. Previous studies had found an association with better human health, although there were some conflicting results. Now, a study combining two cohorts of more than 150,000 people and a meta-analysis of 37 studies involving more than three million volunteers reinforces this association, finding that greater adherence to the diet is associated with lower all-cause mortality. The results are published in the journal Science Advances.

On 22 August, the UN officially declared famine in Gaza, defined as an extreme situation of food insecurity in which there is insufficient access to food to survive, leading to high rates of malnutrition, disease and mortality. The Spanish Society of Epidemiology explains how this situation is technically assessed, as well as the implications of the declaration.

Eating three servings of French fries per week is associated with a 20% increase in the risk of developing type 2 diabetes, but eating similar amounts of potatoes cooked in other ways (boiled, baked, or mashed) does not substantially increase the risk, according to a study published in BMJ. The study, which analyzed the diets of more than 205,000 adults over decades, showed that replacing any form of potato with whole grains was associated with a lower risk of type 2 diabetes.

Intermittent fasting has similar effects to calorie-restricted diets in terms of weight loss, concludes a meta-analysis, published in The BMJ, pooling the results of 99 previous clinical trials. Of three types of intermittent fasting (alternate-day fasting, time-restricted eating and all-day fasting), intermittent fasting has a higher impact on weight reduction compared to continuous energy restriction, the study adds.

In women, high consumption of sugary drinks is associated with an increased risk of oral cavity cancer, according to a study published in JAMA Otolaryngology-Head & Neck Surgery. Among research participants who consumed one or more sugary drinks per day, the rate of these cancers was 5 cases per 100,000 people, compared to 2 cases per 100,000 among those who drank less than one per month. The analysis is based on data from more than 162,000 nurses followed for 30 years in the United States. According to the authors, further studies with larger samples, including men, are needed to validate these results.

Aspartame, a common sweetener used in many sugar-free foods and drinks, affects the cardiovascular health of mice and monkeys, a study claims. Consuming aspartame increases the animals' insulin levels and contributes to the development of atherosclerosis, the buildup of fatty plaque in the arteries, according to the research article published in Cell Metabolism.

Inflammation is all the rage. In fact, anti-inflammatory diets that claim to fight it. This is attested to by best-selling books and influencers, ready to give us the latest tips on how to lose weight, or rather, how to reduce inflammation. But what's the truth in all this, and what does inflammation have to do with being overweight?