The US Food and Drug Administration (FDA) has issued a statement reporting that it has received reports of T-cell tumours in patients who received various CAR-T cell treatments. As quoted in the statement, "although the overall benefits of these products continue to outweigh their potential risks for their approved uses, FDA is investigating the identified risk of T cell malignancy with serious outcomes, including hospitalization and death, and is evaluating the need for regulatory action".

According to research published in the journal Nature Communications, the magnitude 7.8 earthquake that was felt in parts of Turkey and Syria in February this year emitted detectable signals eight months before it struck. Although it is currently not possible to predict the magnitude, time and location of earthquakes in the short term, these results would indicate that some large earthquakes may show a detectable preparation phase. However, the authors admit that, due to the large number of variables, recognising these signals and using them for medium-term earthquake prediction remains a challenge.

The injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well-tolerated, and has a lasting effect that appears to protect the brain against further damage, according to an early-phase trial published today in the journal Cell Stem Cell.

Since mid-October, northern China has reported an increase in influenza-like illness compared to the same period in the previous three years. On 21 November, the media and the ProMED system reported outbreaks of pneumonia of undiagnosed cause in children in northern China. According to the World Health Organization (WHO), it is unclear whether these are related to the overall increase in respiratory infections previously reported by the Chinese authorities or are separate episodes. In a statement, the WHO has officially requested detailed information from China on this increase in respiratory illnesses and outbreaks of childhood pneumonia.

In Spain, both in the child and adult populations, excess weight and obesity are more prevalent among men. Additionally, lower educational levels, lower income, disability, and the presence of individuals with obesity in the household are factors associated with a higher prevalence of excess weight and obesity. These are some of the conclusions drawn from two scientific articles and two complementary reports prepared by the National Center for Epidemiology of the Carlos III Health Institute and the Spanish Agency for Food Safety and Nutrition (AESAN). The data is derived from the ENE-COVID survey, which investigated the seroprevalence of COVID-19 infection in Spain.

Babies' brains specialise in their native language from pregnancy, according to a study carried out in France. The research team used encephalograms to measure the brain activity of 33 infants born to French-speaking mothers while listening to a story in French, English or Spanish. The results provide "the most compelling evidence to date that language experience already shapes the functional organization of the infant brain, even before birth," the authors write in Science Advances.

A fatty acid present in the meat and dairy products of grazing animals, such as cows and sheep – trans-vaccenic acid (TVA) – enhances the ability of CD8+ T cells to infiltrate tumors and eliminate cancer cells, according to a new study conducted by researchers from the University of Chicago (USA), published today in the journal Nature.

Apps developed to treat depression may be beneficial in the management of severe and moderate cases. This is the conclusion of a review and meta-analysis that included 13 studies with up to 16 different apps. The results are published in the journal JAMA Network Open.

The European Commission will renew the authorisation of the pesticide glyphosate in the European Union for 10 years, subject to "new restrictions and conditions". Following EU procedure, the announcement was made after member states failed to reach the majority required to renew or refuse approval.

A dietary shift from animal-based foods, such as red or processed meat and eggs, to plant-based foods, such as nuts, pulses and whole grains, is associated with a reduced risk of death and diabetes or cardiovascular disease. For example, replacing 50 grams of processed meat per day with 28-50 grams of nuts is associated with a 27% decrease in cardiovascular risk. These are the conclusions of a systematic review of 37 studies published in the journal BMC Medicine.