A team of researchers in South Korea has analysed the oral and faecal microbiomes of just over 507 volunteers and has concluded that, in patients with gastric and colorectal cancer, there is a greater transfer of microbes from the mouth to the gut. Furthermore, not only does this transfer differ between tumour types, but, according to their findings, an analysis based on oral samples is capable of detecting colorectal cancer with greater sensitivity than the standard faecal occult blood test. However, “before it can be used in practice, clinical trials would need to be carried out in real-world screening populations”, the authors explain. The study is published in the journal Cell Host & Microbe.

A team of researchers in Germany has analyzed various factors to estimate the potential annual forest area burned in Europe by the end of the century. According to their findings, in a low-emissions scenario, the area burned would increase by 39%, while it could almost triple in a high-emissions scenario. However, improvements in fire management have the potential to significantly limit these projections. The authors, who published their work in the journal Global Change Biology, point out that “while reducing emissions is essential to lessening the impact of fires, the results also show that improvements in prevention, early detection, and firefighting play a key role in helping to reduce the extent of the affected area."

In a press release, the pharmaceutical companies Moderna and Merck have announced the results of their ongoing Phase 3 INTerpath-001 clinical trial, which is evaluating an mRNA vaccine (intismeran) in combination with pembrolizumab in patients with completely resected Stage IIB–IV melanoma. There is as yet no scientific publication containing data on improved survival or a reduction in recurrence.

An international team has analyzed sea surface temperatures in the Atlantic Ocean and at various points in the Mediterranean Sea. The analysis, published by World Weather Attribution (WWA), shows that this year's temperatures have been extraordinary, both in their intensity and how early they have reached such magnitude. This behavior is not only having an ecological impact on marine life, the authors state, but could also exacerbate potentially destructive regional climate events like those that occurred in Valencia in 2024.

Although it is well known that physical activity can help reduce the risk of dementia, a study published inThe Lancet Public Health now suggests that context matters. According to a meta-analysis incorporating data from more than four million people, leisure-time exercise — such as walking, cycling, running, swimming or playing sports — is associated with a substantially lower risk of developing dementia. Conversely, physical activity carried out as part of one’s job is linked to a higher risk of developing the condition. As this is an observational study, it does not allow us to determine whether work causes dementia.

The plague outbreak recorded in the Mallorcan towns of Son Servera and Capdepera in 1820, with an overall case-fatality rate of 78 per cent, has historically been regarded as an episode of bubonic plague, a zoonotic disease normally acquired through the bite of an infected flea carried by animals such as rodents. Now, a study published in the journal PNAS, which has drawn on hundreds of contemporary reports—including daily death tolls—and epidemiological models, suggests that the disease was not transmitted exclusively by infected rodents, but was spread from person to person. Therefore, according to the authors, it may have been the pneumonic or septicaemic forms of the plague.

We hadn’t seen a total solar eclipse on the Iberian Peninsula since 1912, and this Wednesday, just before sunset, the celestial bodies aligned once more. That perfect cosmic dance between the Sun, the Moon and the Earth could be seen from numerous regions across Spain. Among the millions of people who observed the phenomenon in Spain, eclipse experts share their impressions with SMC Spain.

A study published in Science Advances has shown that areas affected by extreme wildfires – characterised by rapid spread and great difficulty in extinguishing them – have lower tree cover and reduced resilience compared to less intense fires, which may lead to long-term changes in vegetation. The team analysed 32.1 million hectares of coniferous forest in Canada and the western United States that were affected by fires between 2012 and 2023. Of this area, more than a third was burnt by extreme fires. In these cases, they observed that the faster the fire front advances, the greater the size and severity of the fire and the greater the distance from seed sources for the surviving trees, paving the way for long-term changes in vegetation.

Statins are used to prevent atherosclerotic cardiovascular disease (ACD), a specific type of cardiovascular disease caused by the build-up of fatty plaque inside the arteries, which can lead to heart disease or stroke. A study published in The Lancet Healthy Longevity analysed the effect of stopping statins in adults aged 75 and over who were taking them preventatively, that is, without a history of atherosclerotic cardiovascular disease. The results showed that discontinuing treatment was no worse than continuing it in terms of all-cause mortality over a three-year period. According to the authors, these results support individualised decision-making regarding the discontinuation of statin treatment in older people, rather than a blanket recommendation to stop taking them.

A person’s waist circumference is a better indicator of the risk of cardiovascular disease than body mass index (BMI) alone, according to a study published in the Journal of the American College of Cardiology. BMI has been used to determine overweight or obesity, common risk factors for heart disease, but this research — which analysed data from nearly 260,000 people with an average follow-up of 20 years — shows that failing to take waist circumference (WC) or the waist-to-hip ratio (WHR) into account can lead to an incorrect assessment of the risk of cardiovascular disease.