Reaction: mice still show allergies when exposed to various microbes, which challenges the hygiene hypothesis
A new study in mice, published in Science Immunology, challenges the so-called 'hygiene hypothesis', the idea that a contributing factor to allergies is that there is an under-stimulated immune system that has not seen enough exposure to germs from current hygienic conditions. In the research, laboratory mice still developed allergies when exposed to various microbes.