Complutense University of Madrid

In the context of World AIDS Day, which is celebrated on 1 December, it is essential to reflect on one of the most urgent challenges in the fight against this disease: HIV in the paediatric population. A project led by the Complutense University of Madrid seeks to reduce paediatric mortality by training research leaders in sub-Saharan Africa and applying technology and innovation.

At least two hominin species - Homoerectus and Paranthropus boisei- coexisted in Kenya's Turkana Basin around 1.5 million years ago, a study published in Science confirms. The authors describe the first physical evidence of this coexistence in the form of footprints, found at several sites in the area.

Until now, memories have been explained by the activity of neurons that respond to learning events and control recall. A study published in Nature changes this theory by showing that non-neuronal cells in the brain called astrocytes - star-shaped cells - also store memories and work in concert with clusters of connected neurons called engrams to regulate the storage and retrieval of memories.

The restriction of sugar during the first 1,000 days of life, starting from gestation, may protect against diabetes and hypertension in adulthood, according to a study published in Science. The research uses data from sugar rationing implemented in the United Kingdom after World War II. The findings highlight the long-term benefits of reduced sugar intake during early development.

US researchers have published a model showing that ice in the mid-latitudes of Mars could allow photosynthetic life to develop. Its thickness and composition would attenuate harmful ultraviolet radiation, but allow sufficient visible light to pass through. The work is published in the journal Communications Earth & Environment.

The Royal Swedish Academy of Sciences has awarded the Nobel Prize in Chemistry 2024 on the one hand to David Baker for computational protein design, which makes it possible to construct proteins with functions not present in nature. On the other hand, jointly to Demis Hassabis and John M. Jumper of Google DeepMind, for the development of AlphaFold2, which allows the structure of the 200 million known proteins to be predicted at high speed. 

A study has analyzed changes in the Earth's average global surface temperature over the past 485 million years and has discovered oscillations ranging from 11°C to 36°C, representing a variation of up to 25°C. The research concludes that temperatures during the Phanerozoic underwent more fluctuations than previously thought and shows a correlation between CO₂ and changes in Earth's temperature. The article, published in the journal Science, combines thousands of data points with a modeling method used for weather forecasting.

Hormonal therapy to treat breast cancer is associated with a lower risk of Alzheimer's disease and dementia in women over 65, a study says. The retrospective analysis is based on data from more than 18,000 women with breast cancer in the US: two-thirds of them had received hormone therapy and one-third had not. The "protective effect" of hormone therapy declines with age and varies by ethnicity, adds the article published in JAMA Network Open. 

Five out of ten potential treatments move from animal studies to human studies; four to randomised controlled clinical trials; and one in 20 moves on to approval by regulatory agencies, an analysis estimates. Concordance between positive results in animals and in clinical studies is 86%, according to the study, published in PLoS Biology, which pools the findings of 122 published studies on 54 different human diseases.  

ESA's ExoMars and Mars Express missions have for the first time detected ice near the equator of Mars, specifically in the Tharsis volcanoes, an area of the planet where it was thought impossible to exist. According to the researchers, who publish the results in the journal Nature Geoscience, such findings are important for habitability and future human exploration.