Scientists

Scientists

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An antiviral already on the market could be more effective than oseltamivir (Tamiflu) against avian influenza

A team in the US has tested the efficacy of baloxavir, an antiviral already on the market for treating common flu, against avian influenza in mice. The results, published in the journal Nature Microbiology, show that it is more effective than the currently recommended oseltamivir (Tamiflu) except when the infection is via the mouth, in which case it is equally effective. According to the authors, baloxavir ‘could be considered for the potential treatment of serious H5N1 virus infections in humans’.

‘Micro-lightning' in water droplets could have generated molecules that were key to the origin of life

Until now, one hypothesis suggested that life on Earth could have arisen from lightning striking a body of water. However, a new study claims that the synthesis of molecules necessary for the emergence of life could have originated from ‘micro-lightning’ in water droplets. According to the study, published in Science Advances, the formation of organic compounds with carbon-nitrogen bonds from gas molecules could be a possible mechanism for creating the basic components of life on the early Earth.

Structure of a protein linked to Parkinson's disease described

Discovered years ago, PINK1 is a protein directly linked to Parkinson's disease, but it was not known what it looks like, how it binds to the surface of damaged mitochondria or how it is activated. A study published this week in Science has for the first time determined the structure of this protein. The authors suggest that this new information could help in finding new treatments.

 

Study shows that in women, high consumption of sugary drinks was associated with an increased risk of oral cavity cancer

In women, high consumption of sugary drinks is associated with an increased risk of oral cavity cancer, according to a study published in JAMA Otolaryngology-Head & Neck Surgery. Among research participants who consumed one or more sugary drinks per day, the rate of these cancers was 5 cases per 100,000 people, compared to 2 cases per 100,000 among those who drank less than one per month. The analysis is based on data from more than 162,000 nurses followed for 30 years in the United States. According to the authors, further studies with larger samples, including men, are needed to validate these results.

Researchers design a spinal neuroprosthesis that interacts with robotic devices in people with paralysis

An international team has developed an implantable neuroprosthesis in the spinal cord that can interact with various robotic devices and enable movements in people with severe spinal cord injuries. The study, conducted in nine patients, showed that the device facilitated robotic-assisted walking and cycling and promoted neuromuscular activation. The results are published in the journal Science Robotics.  

Researchers discover how extrachromosomal DNA circles contribute to the aggressiveness of pancreatic cancer

Extrachromosomal DNA circles are structures that appear floating in the nucleus of cells in some tumours and are associated with a poor prognosis. Now, an international team has studied the mechanism by which they could contribute to the aggressiveness of pancreatic cancer. The circles may contain an oncogene called Myc that promotes growth. Furthermore, their quantity increases or decreases to adapt to the environment. Although they were only observed in 15% of the cases studied, the discovery could open up new possibilities for treatment, according to the authors. The results are published in the journal Nature.

The oldest human ‘face’ in Western Europe has been discovered

A fragment of a human face discovered in 2022 at the Sima del Elefante site in the Sierra de Atapuerca (Burgos) and dated to between 1.1 and 1.4 million years ago represents the oldest known face in Western Europe. The fossil, nicknamed ‘Pink’, does not belong to Homo antecessor, but has been provisionally catalogued as Homo affinis erectus. The find, which is published in the journal Nature, could indicate that Western Europe was populated by at least two species of hominids during the Early Pleistocene: Homo affinis erectus and, later, Homo antecessor.

The European Commission presents its proposal on the Critical Medicines Act to guarantee supply and reduce external dependence

On Tuesday the European Commission presented the draft of its new Critical Medicines Act. Its objective is to address the serious shortage of medicines and healthcare products, reduce external dependence on critical medicines and ingredients — especially from Asia — and guarantee the supply of affordable medicines in the European Union.