Scientists

A clinical trial funded by Pfizer has tested a new influenza vaccine based on messenger RNA (mRNA). The phase 3 trial included more than 18,000 people aged 18 to 64, half of whom received the new compound and the other half a conventional vaccine. The results indicate that the mRNA vaccine was more effective, but it also caused more adverse reactions: for example, 5.6% of the volunteers who received it developed a fever, compared to 1.7% of those who received the conventional vaccine. The study is published in the journal NEJM. 

In a sample of academic articles retracted by medical journals, the proportion of female authors is lower than the overall share of female researchers in these fields. "The underrepresentation of women among retracted authors, particularly for misconduct-related retractions, may reflect systemic gender imbalances in academia rather than differences in scientific integrity," writes the author of the study in PLoS One. His analysis, based on 878 retracted publications in nine clinical areas, estimates that 16.5% of the first authors of retracted papers were female, while the proportion of first authors of biomedical publications exceeds 40%.

Around 840 million women worldwide — nearly one in three — have been victims of physical, psychological or sexual violence by their partner or have suffered sexual violence outside of their relationship, a figure that has barely changed since 2000. This is one of the conclusions of a report led by the World Health Organisation (WHO) that analyses data from 168 countries between 2000 and 2023. For the first time, the study includes estimates of sexual violence outside of intimate relationships: 263 million women have suffered this type of assault since the age of 15, a figure that, according to experts, is well below the actual number.

Three articles with Spanish participation, published in The Lancet, review the evidence that ultra-processed foods are worsening diet quality and displacing the consumption of fresh and minimally processed foods. Furthermore, they warn that their consumption is linked to a higher risk of multiple chronic diseases. According to the authors, who also review the associated policies and commercial factors, only a coordinated global response can combat the strategy of the companies that market these products.

According to a study compiling data from 10,000 marine animal necropsies, 35% of birds, 12% of mammals, and 47% of turtles examined had ingested macroplastics, causing death in 1.6%, 0.7%, and 4.4% of these animals, respectively. The types of plastic that pose the greatest risk are rubber for birds, soft plastics and fishing debris for mammals, and hard and soft plastics for sea turtles, concludes this study published in PNAS.

According to a study published in the journal JAMA Health Forum, the use of the benzodiazepine lorazepam by the character Victoria Ratliff in the series The White Lotus was associated in the United States with an increase in Google searches for this medication, including queries about how to obtain it online. The series generated 1.6 million more searches than usual over a 12-week period. Although the study reflects searches for information and not actual consumption, the abuse of anti-anxiety drugs is a fact: illegal sales of benzodiazepines have increased in the United States, and Spain leads the rankings in terms of consumption.

There is no solid scientific evidence that alterations in the gut microbiota cause autism, according to an opinion piece published in the scientific journal Neuron. The research supporting this hypothesis—observational studies and clinical trials in humans, as well as mouse models—has both conceptual and methodological shortcomings, the authors write.

A review conducted by the Cochrane Collaboration analyzed the effects of colchicine—a medication commonly used to treat some rheumatic diseases—on people who had already experienced a cardiovascular event. The review included 12 clinical trials with more than 23,000 patients and concluded that colchicine reduces the risk of stroke or heart attack in these individuals. Overall, for every 1,000 people treated, there were 9 fewer heart attacks and 8 fewer strokes compared to those who did not take the medication, with no apparent serious side effects.

The Global Carbon Budget's projections for 2025 estimate that carbon dioxide (CO₂) emissions from fossil fuels will reach a new all-time high of 38.1 billion tons, an increase of 1.1% over 2024. This global report—now in its 20th edition and to be presented at COP30 in Belém, Brazil—estimates that emissions in the United States and the European Union will grow this year, in contrast to the decline in previous years, partly due to weather conditions and higher energy consumption. The study is published in the journal Earth System Science Data in preprint format.

At the current rate of carbon dioxide emissions, the 1.5°C temperature increase limit set in the Paris Agreement will be exceeded in four years. This is one of the predictions of the Global Carbon Budget 2025, the global report on the carbon balance, now in its 20th edition, which will be presented at COP30 in Belém (Brazil). Pep Canadell, one of its authors, analyzed its findings at a briefing organized by SMC Spain.