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New variant of mpox confirmed in Sweden

Sweden's public health agency issued a statement on Thursday indicating that a person has been diagnosed with mpox - formerly called monkeypox - caused by variant clade I. According to the Swedish agency, this is the first case of this variant to be diagnosed outside the African continent. The person would have been infected during a stay in a part of Africa where there is an outbreak of this variant of mpox, according to the statement. The announcement comes a day after the World Health Organisation declared the mpox outbreak a public health emergency of international concern.

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One in four people with brain-damage who do not respond to stimuli may have some degree of consciousness

An international team of researchers has studied 241 brain-damaged people apparently unable to respond to external stimuli. Using techniques such as functional magnetic resonance imaging and electroencephalogram, they have detected signs of brain activity in 25 % of them that, according to the authors, ‘suggest that they may be interacting with the outside world’. The results are published in the journal NEJM

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Keto diet improves results of pancreatic cancer drug in mice

A ketogenic diet improves the results of a pancreatic cancer therapy in mice, according to a study published in Nature. The US research team fed the animals a high-fat, low-carbohydrate diet before administering them a new drug, currently in clinical trials; in the absence of glucose, the body converts fat into ketone bodies. The drug blocks the metabolism of fat - the cancer's only source of energy while the mice are on this diet - and slows the growth of pancreatic tumours. 

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Adaptation measures in Europe prevented 80% of heat-related deaths in 2023

Heat-related mortality in Europe would have been 80% higher last year without recent adaptation measures to rising temperatures, such as changes in infrastructure and public behaviour, according to a study led by ISGlobal. The study, published in Nature Medicine, estimates that more than 47,000 deaths were related to the heat in 35 European countries in 2023 - the second highest number in the 2015-2023 period, behind 2022. Heat-related mortality was highest in southern European countries including Spain (175 deaths per million people), Italy (209) and Greece (393). 

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Classical music's antidepressant mechanism in the brain studied

A brain study of 23 people with treatment-resistant depression while they listen to classical music has identified the antidepressant mechanisms of this music. Using intracranial recordings and electroencephalogrammes, the researchers concluded that listening to classical music synchronises neuronal oscillations between the auditory cortex - responsible for processing sensory information - and the reward circuit - responsible for processing emotional information. "The improvement of depressive symptoms was not linked to the emotion of the music itself but was correlated with the patient’s level of music enjoyment," says the study published in Cell Reports.

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