Scientists

Scientists

For science to make the news in a rigorous and attractive way, good sources are needed. Because access to scientific knowledge is a citizen's right.

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Advocates call for earlier screening for gestational diabetes

Management of gestational diabetes should include earlier testing during pregnancy, as well as testing in the postpartum period, according to a series of papers published in The Lancet. Screening is usually done during the second half of pregnancy, but the authors note that diagnosis and treatment is especially beneficial before 14 weeks of pregnancy. 

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Two clinical trials test immunomodulator to improve cancer immunotherapy

Cancer immunotherapy, and in particular the so-called checkpoint inhibitors, have improved the prognosis of several types of tumours. However, they are not effective in everyone. Two early-stage clinical trials have tested the addition of a type of immunomodulator to this therapy in patients with lung cancer and Hodgkin's lymphoma, with apparent good results. The results are published in the journal Science.  

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Carbon stored in plants more ephemeral than previously thought

Carbon stored globally by plants is shorter-lived and more vulnerable to climate change than previously thought, according to a study published in Science. This has implications for nature's role in climate change mitigation, including the potential for carbon removal projects such as mass tree planting. The research reveals that existing climate models underestimate the amount of carbon dioxide (CO2) that vegetation absorbs globally each year, but overestimate how long that carbon stays there. 

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Mosquito-borne diseases: an increasing risk in Spain

International health organisations are warning about the spread in Europe of mosquito species that transmit diseases such as dengue fever. In Spain, where they are already widespread across much of the country, the Centro de Coordinación de Alertas y Emergencias Sanitarias (CCAES) warns of the risk of West Nile virus, and says that the summer is expected to be complicated. In this guide, we bring together information to understand this public health issue. 

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A single copy of a protective gene variant helps delay early Alzheimer's disease

A family of more than 1,000 members with origins in Colombia has a mutation called "paisa" that leads to the development of Alzheimer's disease. In 2019, an added mutation in the apoE gene called "Christchurch" was described as conferring strong protection to an individual carrying two copies of it. Now, a study has found that 27 family members carry a single copy and that it is also associated with some degree of protection. According to the authors, who publish their findings in the journal NEJM, the discovery could be used to develop new treatments for the disease. 

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Study compares safety of autonomous vehicles versus human-driven vehicles

A study has compared data from 2,100 accidents involving autonomous vehicles and just over 35,000 accidents involving human-driven vehicles between 2016 and 2022, mainly in California (US). Their findings are that autonomous vehicles are safer in many driving situations, but suffer more accidents in situations such as turning times or during dawn and dusk. The results are published in the journal Nature Communications.  

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Clinical trial compares efficacy of e-cigarettes and varenicline for smoking cessation

A clinical trial in Finland has compared the effectiveness of nicotine-containing e-cigarettes and varenicline tablets for smoking cessation. The study, which included 458 participants, found no difference between the two strategies at six months. However, after one year, only varenicline was found to be clearly more effective than placebo. The results are published in the journal JAMA Internal Medicine.  

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Malaria compound to treat polycystic ovary syndrome

Artemisinins, plant-based antimalarials, may serve as a treatment for polycystic ovary syndrome - which affects millions of women worldwide and can lead to infertility - according to a new study published in Science. The compounds suppressed ovarian androgen production in rodents, as well as in a small cohort of 19 human patients for 12 weeks, leading to more regular menstrual cycles without side effects. 

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