Management of gestational diabetes should include earlier testing during pregnancy, as well as testing in the postpartum period, according to a series of papers published in The Lancet. Screening is usually done during the second half of pregnancy, but the authors note that diagnosis and treatment is especially beneficial before 14 weeks of pregnancy.
Carbon stored globally by plants is shorter-lived and more vulnerable to climate change than previously thought, according to a study published in Science. This has implications for nature's role in climate change mitigation, including the potential for carbon removal projects such as mass tree planting. The research reveals that existing climate models underestimate the amount of carbon dioxide (CO2) that vegetation absorbs globally each year, but overestimate how long that carbon stays there.
Cancer immunotherapy, and in particular the so-called checkpoint inhibitors, have improved the prognosis of several types of tumours. However, they are not effective in everyone. Two early-stage clinical trials have tested the addition of a type of immunomodulator to this therapy in patients with lung cancer and Hodgkin's lymphoma, with apparent good results. The results are published in the journal Science.
International health organisations are warning about the spread in Europe of mosquito species that transmit diseases such as dengue fever. In Spain, where they are already widespread across much of the country, the Centro de Coordinación de Alertas y Emergencias Sanitarias (CCAES) warns of the risk of West Nile virus, and says that the summer is expected to be complicated. In this guide, we bring together information to understand this public health issue.
The third part of the National Plan for Surveillance and Control of Vector-borne Diseases is presented today, focusing on ticks, parasitic mites that cause serious diseases. Of these, the two of greatest concern in Spain are Lyme disease and Crimean-Congo haemorrhagic fever. Cases are expected to increase, but so far there has been no surveillance. International health authorities have also warned of the risks of Lyme disease in connection with the European Football Championship being held in Germany in recent weeks.
A family of more than 1,000 members with origins in Colombia has a mutation called "paisa" that leads to the development of Alzheimer's disease. In 2019, an added mutation in the apoE gene called "Christchurch" was described as conferring strong protection to an individual carrying two copies of it. Now, a study has found that 27 family members carry a single copy and that it is also associated with some degree of protection. According to the authors, who publish their findings in the journal NEJM, the discovery could be used to develop new treatments for the disease.
A study has compared data from 2,100 accidents involving autonomous vehicles and just over 35,000 accidents involving human-driven vehicles between 2016 and 2022, mainly in California (US). Their findings are that autonomous vehicles are safer in many driving situations, but suffer more accidents in situations such as turning times or during dawn and dusk. The results are published in the journal Nature Communications.
A clinical trial in Finland has compared the effectiveness of nicotine-containing e-cigarettes and varenicline tablets for smoking cessation. The study, which included 458 participants, found no difference between the two strategies at six months. However, after one year, only varenicline was found to be clearly more effective than placebo. The results are published in the journal JAMA Internal Medicine.
Starting June 17, the Ministry of Health will begin using a new, more rigorous alert system based on 182 meteosalud zones instead of 52 provinces. The aim is to make the plan more effective, inform the population when necessary, and ultimately save lives.
Five out of ten potential treatments move from animal studies to human studies; four to randomised controlled clinical trials; and one in 20 moves on to approval by regulatory agencies, an analysis estimates. Concordance between positive results in animals and in clinical studies is 86%, according to the study, published in PLoS Biology, which pools the findings of 122 published studies on 54 different human diseases.