In the year 2023, Science magazine has chosen the development and discovery that GLP-1 medications, agonists of the glucagon-like peptide-1, can mitigate health issues associated with obesity as the most important scientific breakthrough. Similarly, Nature magazine has selected biochemist Svetlana Mojsov, a key figure in the discovery of GLP-1, as one of the top ten scientists of the year.
A meta-analysis by the University of Valencia has studied the links between leisure reading habits on digital devices and the reading comprehension of students of different ages. The research - which is based on 25 studies published between 2000 and 2022 involving some 470,000 students from different countries - concludes that in the early stages (primary and 1st and 2nd ESO in the Spanish case) there were small negative relationships between digital leisure reading and reading comprehension, while in later stages (3rd and 4th ESO, baccalaureate and university) the relationship became slightly positive. The research is published in Review of Educational Research.
An international team, led by the Hospital Clínic-IDIBAPS in Barcelona together with King's College London (UK) and Dalhousie University (Canada), has published the largest meta-analysis to date studying the risk of children of people with mental disorders developing the same, or another type of disorder. The study included more than three million children of parents with different types of disorders and more than 20 million people as a control population. The results, published in the journal World Psychiatry, indicate that, overall, the former have a 1.5 to 3 times higher risk of developing a disorder in their lifetime. According to the authors, in the case of bipolar, depressive or anxiety disorders, the risk of their offspring suffering from some type of disorder is more than 50%.
Nine studies published today in the journal Nature present the most comprehensive and detailed characterization of the mouse brain. The findings reveal the structure and organization of the brain, the function of individual brain cells, and neural circuits. According to the authors, these investigations serve as a tool to delve into the development and evolution of mammalian brains, and how the organization of different types of cells could contribute to neurological disorders in humans.
After an intense night of negotiations in Dubai (United Arab Emirates), the countries participating in COP28 reached a historic agreement by mentioning for the first time "moving away from fossil fuels" in the Global Stocktake document - the assessment of progress made towards achieving the climate goals set out in the Paris Agreement. The agreement comes after the first draft presented by the presidency did not make this mention - it referred only to "reducing consumption and production" of these fuels - which was described as "unacceptable" by countries such as Spain.
Intimate partner violence is associated with an increased risk of depression and miscarriage, according to a systematic review of the scientific literature published since 1970. Sexual abuse in childhood is associated with an increased risk of alcohol use disorder and self-harm, says the study published in Nature Medicine. According to its authors, this analysis of 229 previous studies reveals that intimate partner violence and childhood sexual abuse have a more extensive impact on health than previously described.
Behind any study that hits the media with eye-catching headlines there are usually numbers to back it up. Analysing the statistics of a study is one of the greatest challenges in communicating any finding with rigour.
After lengthy negotiations, the European Commission, the European Parliament and the Council of the EU - which represents the member states - reached a provisional agreement last night on the content of the 'AI Act', the future law that will regulate the development of artificial intelligence in Europe, the first in the world. The agreement limits the use of biometric identification systems by security forces, includes rules for generative AI models such as ChatGPT and provides for fines of up to 35 million euros for those who violate the rules, among other measures. The text must now be formally adopted by the Parliament and Council before it becomes EU law.
A review of epidemiological data examines the physical and psychological complications that occur after childbirth in the medium and long term. More than a third of women reported lasting, and often neglected, health problems six weeks after childbirth. The most common complaints were: pain during sexual intercourse (35%), lower back pain (32%), urinary incontinence (8-31%), anxiety (9-24%), anal incontinence (19%), depression (11-17%) or significant fear of childbirth (6-15%). In their paper, published today in the journal The Lancet Global Health as part of a special series, the authors stress the importance of providing comprehensive health services beyond six weeks postpartum.
A study of more than 5,000 patients has developed a method to predict the biological age of our organs. They have analysed more than 4,000 proteins present in the blood and used machine learning models adapted to 11 different organs. According to the authors, almost 20 % of the population has accelerated organ ageing, which in many cases is associated with an increased risk of mortality of between 20 and 50 %. The results are published in the journal Nature.