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CAR-T therapy tested to treat childhood brain tumours considered incurable

CAR-T cell-based treatments have been successful against some blood tumours, but are much less effective for solid tumours. A phase 1 clinical trial has tested their use in 11 children and young adults with diffuse midline glioma, a tumour of the nervous system that is considered incurable. The results, published in the journal Nature, indicate that the treatment improved functional status in nine of the 11 patients. One of the four who showed a strong response is still healthy four years later.

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Pep Canadell: ‘Trump can stop the US from cutting emissions, but not reverse the progress made in decarbonisation’

The largest carbon balance report shows that carbon dioxide emissions have not yet peaked and are projected to reach 37.4 billion tonnes by 2024. In a briefing organised by SMC Spain, Pep Canadell, one of the people in charge of the Global Carbon Budget 2024, analysed these data and what Donald Trump's return as US president means for climate action in the framework of COP29 in Baku.

 

 

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Fossil CO2 emissions to rise to 37.4 billion tonnes by 2024, says major carbon balance report

There are still no clear signs that global fossil carbon dioxide (CO2) emissions have peaked, according to the 2024 Global Carbon Budget. The report - which is published in the journal Earth System Science Data in preprint format and will be launched at COP29 in Baku - estimates that these emissions will grow by 0.8% this year compared to 2023, to 37.4 billion tonnes of CO2. If this rate continues, there is a 50% chance that global warming will exceed the 1.5°C limit in six years.

 

 

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Study looks at men's problems with fatherhood due to lack of information and emotional support

Men often struggle with the transition to fatherhood due to a lack of information and emotional support targeted to their needs, suggests a review of the available qualitative evidence, published in the open access journal BMJ Open. The researchers say there needs to be a greater focus on clinical practice, antenatal services and research into men's unique experiences during the perinatal period, which encompasses pregnancy and the first 12 months after birth.

 

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The wildland-urban interface, which is vulnerable to fires, has grown by 35% since 2000

The interface between wildland and urban areas - areas that are at risk of devastating fires - has grown by 35.6 per cent between 2000 and 2020, says a study based on satellite data. The increase has accelerated since 2010 due to growing urbanisation, reaching 1.93 million square kilometres worldwide, adds the study published in Science Advances.

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CO2 emissions caused by private flights increased by 46 % between 2019 and 2023

Private flights are used by approximately 0.003 % of the world's population, but the CO2 emissions they released in 2023 were equivalent to 1.8 % of those of all commercial aviation. These are the conclusions of a study published in the journal Communications Earth & Environment, which estimates that emissions from private flights increased by 46 % between 2019 and 2023. Almost half of them covered a distance of less than 500 kilometers.

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What to expect from the Baku Climate Summit

Next Monday sees the start of COP29 in Baku, the capital of Azerbaijan, a summit marked by Donald Trump's victory as president of the United States on Tuesday. His denial of climate change and his commitment to fossil fuels during his previous term in office will weigh down a meeting from which no major agreements are expected and from which experts are calling for greater ambition. 

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Astrocytes, like neurons, would also store memories

Until now, memories have been explained by the activity of neurons that respond to learning events and control recall. A study published in Nature changes this theory by showing that non-neuronal cells in the brain called astrocytes - star-shaped cells - also store memories and work in concert with clusters of connected neurons called engrams to regulate the storage and retrieval of memories.

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What impact will Donald Trump's victory have on climate change?

For the second time, Donald Trump has won yesterday's US presidential election. The Republican leader returns to the White House four years later, after a first term in office with climate policies that ran counter to scientific evidence. Among other controversial measures, he abandoned the Paris Agreement and repeatedly denied the existence of climate change. 

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