The Science group is simultaneously publishing four papers (two in the journal Science, one in Science Immunology and one in Science Translational Medicine) that include advances in a sequential vaccination strategy for an effective HIV vaccine. The methods employed aim to obtain broad-spectrum neutralising antibodies and one of the proposals is already in clinical trials. 

A team of physicists led by Harvard University (USA) has succeeded in linking two quantum memory nodes 35 kilometres apart using existing fibre optics in the Boston area (USA). This is the longest distance achieved to date. According to the authors, who publish their results in the journal Nature, ‘demonstrating that quantum network nodes can intertwine in the real-world environment of a busy urban area is an important step towards practical networking between quantum computers’. 

A research team has discovered a type of cell that appears to be linked to parental care in Oldfield mice, a monogamous species. These cells are not present in Deer mice, other rodents of the same genus that engage in promiscuous behaviour. The results "provide an example by which the recent evolution of a new cell type in a gland outside the brain contributes to the evolution of social behaviour," the authors conclude in their paper, published in Nature. 

Twenty-three per cent of the world's population over the age of 69 will be living with acute heat exposure by 2050, compared to 14 per cent in 2020, according to a study published in Nature Communications. The research highlights southern Europe, parts of North and South America, Southeast Asia and all of Australia as areas of ‘increasing stress’, where higher heat exposure overlaps with an increasingly ageing population. The effects will be most severe in Asia and Africa, according to the study. 

An international group of researchers analyzed multiple data sets with current measurements and historical reconstructions. Their research concludes that, in the extratropical regions of the Northern Hemisphere (including Europe), the summer of 2023 was the warmest in 2,000 years. The authors published the results in the journal Nature. 

A review article published in Patterns claims that many artificial intelligences have already learned to cheat humans, even those trained to be honest. They cite as an example Meta's CICERO model, which wins by playing dirty Diplomacy. The researchers describe potential risks in problems related to security, fraud and election rigging, and call on governments to urgently develop strict regulations. 

A new Cochrane review has found that taking zinc may help reduce the duration of cold symptoms by about two days, although the authors point out that the evidence is inconclusive and that possible benefits need to be weighed against side effects. 

People who eat more ultra-processed foods have a "slightly higher" mortality rate, according to an analysis published in The BMJ. The study analysed data from more than 110,000 people followed up for over 30 years in the United States. The correlation between ultra-processed food intake and all-cause mortality was strongest for the meat, poultry and seafood group. 

Genetic forms of Alzheimer's are considered to be those in which certain variants of a gene inevitably lead to the disease over time. Until now, only rare alterations in three genes were considered as such. A group of researchers led by the Hospital de Sant Pau in Barcelona has proposed a new, much more frequent form. After analysing data from more than three thousand donated brains and clinical data from more than ten thousand patients, they found that almost all people who carry two copies of the ApoE4 variant in the ApoE gene, which was previously only considered a risk factor, also end up developing the disease.They publish the results in the journal Nature Medicine.  

Hurler syndrome is a rare and very serious disease caused by an enzyme deficiency, which results in a wide variety of signs and symptoms. Treatment with bone marrow transplantation helps to alleviate some of them, but has little effect on skeletal disorders. Now, a phase I/II trial has tested an autologous transplant of blood stem cells corrected by gene therapy in eight patients. The results, published in the journal Science Translational Medicine, suggest that the treatment is more effective and could also improve these types of disorders.