The World Health Organisation (WHO) has announced that a 59-year-old man infected with the H5N2 avian influenza virus died in Mexico on 24 April. This is the first confirmed human infection with the virus. The patient had multiple underlying medical conditions and had been bedridden for three weeks for other reasons before showing symptoms. The source of infection is unknown. The WHO assesses the risk to the general population as low. 

The Lancet Psychiatry publishes the first meta-analysis of the incidence of antidepressant treatment discontinuation symptoms that includes data from more than 20,000 patients collected from 79 randomised controlled trials and observational studies. The study sought to distinguish between symptoms directly caused by medication discontinuation and other ‘non-specific’ symptoms that may be associated with patient or professional expectations (the nocebo effect). The study concludes that one in six to seven patients will experience one or more symptoms directly caused by stopping medication, and one in 35 are likely to experience severe symptoms.  

A higher intake of salt - as measured by the concentration of sodium in urine - is associated with an increased likelihood of atopic dermatitis, says a study published in JAMA Dermatology. The researchers used data on the amount of sodium in urine samples from more than 215,000 people in the UK, collected in a previous study. The authors suggest that restricting salt intake "may be a cost-effective and low-risk intervention" for this skin disease. 

Internet 'addiction' in adolescents is associated with changes in neural networks in their brains, a review of studies has found. The analysis published in PLoS Mental Health brings together the results of 12 previous functional magnetic resonance imaging studies, conducted in young people aged 10-19 in Asian countries (Korea, China and Indonesia).

Drinking alcohol and sleeping in hypobaric conditions - such as those of an aircraft cabin - could be a risk to cardiovascular health, a study warns. Researchers compared a group of 23 people sleeping in a laboratory with another group of 17 people sleeping in a high-altitude chamber, replicating conditions at about 2,400 metres above sea level. The combination of alcohol consumption and hypobaric hypoxia during the simulation "reduced sleep quality, challenged the cardiovascular system and led to extended duration of hypoxaemia," the authors state in the journal Thorax.

Research with Spanish participation concludes that, in European countries, tropospheric ozone pollution from beyond national borders was associated with 88% of ozone-attributable deaths, and only 12% were due to domestic sources. The authors, whose research is published in Nature Medicine, used epidemiological and air quality modelling to quantify the burden of mortality in Europe associated with ozone pollution from various geographical sources. This included more than six million deaths in 813 regions in 35 European countries - including Spain - in the 2015-2017 warm seasons. 

A journalistic investigation by The Investigative Desk (Netherlands) and The BMJ (UK) concludes that tobacco industry-funded studies continue to appear in the most cited medical journals. The team of journalists found hundreds of links in the PubMed database between the medical and pharmaceutical subsidiaries of the big tobacco companies - Philip Morris International, Altria, British American Tobacco, Imperial Brands and Japan Tobacco International - and published medical research. In addition, the research revealed that of 40 journals - the 10 most cited in general medicine and another 30 in areas affected by smoking - only eight had policies prohibiting studies funded in whole or in part by the tobacco industry. 

The classical view describes most cancers as the result of mutations that happen by chance and accumulate over a lifetime. Now, a study claims to break that paradigm. A team of researchers from Stanford University (USA) has described that the genetics we inherit influences the surveillance that our defences do of these mutations, conditioning the type of tumour that can develop and its prognosis. The results, which for the moment refer to breast cancer, are published in the journal Science.  

Combining two types of cameras could enable autonomous vehicles to detect objects accurately and efficiently, say researchers in Switzerland in a study published in Nature. Autonomous vehicles need visual systems capable of detecting fast-moving objects without sacrificing image quality. The system described combines a colour camera with a reduced frame rate - to lower the bandwidth needed to process images - and an event camera, which detects fast movements - such as pedestrians or vehicles - and compensates for the higher latency of the colour camera.  

A study in England has found a link between increased exposure to air pollution during early life and the risk of developing psychotic disorders and depression during youth. In addition, greater exposure to noise during childhood and adolescence was associated with an increased risk of anxiety. The results of the study, which collected data from more than 9,000 people, are published in the journal JAMA Network Open.