In the context of World AIDS Day, which is celebrated on 1 December, it is essential to reflect on one of the most urgent challenges in the fight against this disease: HIV in the paediatric population. A project led by the Complutense University of Madrid seeks to reduce paediatric mortality by training research leaders in sub-Saharan Africa and applying technology and innovation.

Funding has been one of the major obstacles to agreement at the Baku Climate Summit. More sustainable science also depends on how research is funded. It is imperative that research institutions also develop strategies to incorporate more sustainable practices and contribute to climate neutrality.

Most disasters do not occur in isolation, often triggering new challenges before the community has been able to recover. Floods in Valencia pose risks of infections and intoxications, challenges to mental health and to the supply of drugs and food, which affect the vulnerable population the most and must be addressed in a coordinated manner. In the face of such events, the overall strengthening of a country's healthcare system is critical.

The devastating floods in Valencia have reminded us of the crucial role of language in journalism: in the maelstrom of information following the catastrophe, numerous articles have resorted to the expression “natural disaster”, as if the tragedy were a sort of inescapable sentence dictated by nature. The idea that nature acts with intent or malice in causing suffering is a concept that distorts our understanding of these events.

Two of the Nobel Prize winners in Chemistry 2024 are employees of Google DeepMind, who caused significant unrest among their colleagues in May. Hassabis and Jumper announced in *Nature* the results of their AlphaFold 3 model, with applications in drug design; however, they published it in a closed manner, with reviewers not even having access to the system, which contradicts the basic principles of scientific publication. We risk having the transformative potential of AI controlled by big tech companies.

Men and women could develop Alzheimer’s disease through different mechanisms. Understanding these differences is essential to design specific interventions and to treat the disease effectively. In an article published in Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association, a group of researchers, including myself, have highlighted the urgency of adding a sex and gender approach to the studies on this pathology.

August 2003 was the month of the heatwave that killed 70,000 people in Europe. In France, with 14,800 deaths, the Minister of Health resigned, and in Spain, with 6,500, the first prevention plan for the extreme heat was put in motion, which came into force in 2004. Two decades later, campaigns and preventive measures in social services, nursing homes, and hospitals have generated the so-called "heat culture," and although temperatures continue to rise due to climate change, this adaptation is limiting its impact.

Many people don't follow sports events, yet they enjoy the Olympics. Unlike the dominant men's soccer industry, the Olympics offer a wide variety of events for all tastes, with greater visibility of women's sports and a context that makes it easier to connect with the competition narrative, based on an internationalist and humanist spirit. They are proof that sports appeal to everyone because play is part of human essence.

Research published a few days ago in the New England Journal of Medicine (NEJM) found a considerable and hitherto unknown degree of micro- and nanoplastic contamination in human arteries. It was a bit of a surprise that NEJM accepted the paper, as it usually publishes little on the environmental causes of human disease. The good thing is that the publication makes visible, legitimises, stirs up and will encourage other similar work.
 

In a recent publication, we discovered that efforts to monitor genetic diversity in Europe are incomplete and need to be extended to account for potential climate change impacts on species of conservation interest.